Several Foc TR4 effectors, such as SIX proteins (Secreted In Xylem), FoCupin1, cerato‐platanin, M35 family metalloproteinases, FTF1, and OASTL, have been reported to play an important role in fungal penetration, infection, and full virulence (An et al., 2019; Liu et al., 2019; Lorrain et al., 2015; Wang et al., 2020; Yan et al., 2022; Zhang et al., 2021). The gene discussed is NR2C2; the disease is infection.