Although the fact that IL-32 does not have an ortholog in rodents precluded us from analyzing the vast amount of published transcriptomic data on mouse models of neuroinflammation, we found that IL32 transcript levels were indeed upregulated in astrocytes in various types of multiple sclerosis lesions in humans (Fig. 6c) by reanalyzing the comprehensive single-nucleus RNA-seq dataset from Macnair et al. This evidence concerns the gene IL32 and multiple sclerosis.