In the TA, Sesn2 expression was decreased by 50.68% in the shSesn2 group compared with that in the DMD group (p < 0.05, Fig. S3a and S3b), while in the GAS, Sesn2 expression was decreased by 45.45% (p < 0.05, Fig. S3c and S3d). Here, SESN2 is linked to Duchenne muscular dystrophy.