Individual proteins with the greatest numbers of connections to other proteins were EGFR (involved in cancer drug resistance, brain structure and platelet count), CXCL12 (an immune-related chemokine involved in immune surveillance, inflammation response, tissue homeostasis and tumor growth and metastasis), ITGAV (an integrin protein implicated in body height, handedness, dyslexia and albumin/creatinine metabolism), CXCL9 (implicated in T cell function and inflammation) and CD8A (a CD8 antigen implicated in the innate immune system). The gene discussed is CXCL12; the disease is cancer.