Strikingly, 24 h co-culture of activated CD8+ T cells and SU-DHL-4 cells resulted in enhanced DLBCL cell death under all conditions, and such effects were particularly prominent when SU-DHL-4 cells were pre-treated with RGFP966 (Fig. 4B, C). The gene discussed is CD8A; the disease is diffuse large B-cell lymphoma.