Additionally, high-density lipoprotein binding protein (HDLBP) in HCC reduces ferroptosis susceptibility by binding to cytoplasmic ferroptosis-related long non-coding RNA (lncRNA) lncFAL, precluding Tripartite Motif-Containing Protein 69 (TRIM69)-dependent degradation of ferroptosis suppressor protein 1 (FSP1) [52]. The gene discussed is TRIM69; the disease is hepatocellular carcinoma.