To further investigate the impact of S100A10 on HCC in vivo, we injected MHCC97-L cells that were either not transfected, transfected with S100A10-sh-NC, or transfected with S100A10-sh plasmid into NOD-SCID mice to establish an HCC animal model (Fig. 7A). The gene discussed is S100A10; the disease is hepatocellular carcinoma.