Previous studies have shown that the higher Keap1 expression is closely related to longer progression‐free survival in non‐small cell lung cancer.[27] However, recent studies have shown that higher Keap1 protein expression levels are closely related to lower survival time in colorectal cancer.[28] In this study, we used a HCC liver tissue microarray to detect the expression of Keap1 and found that Keap1 expression in HCC tissues was higher than in para‐carcinoma tissues (Figure 2B). This evidence concerns the gene KEAP1 and colorectal cancer.