Several studies have reported that the PD‐1/PD‐L1 axis may regulate host immune responses to SARS‐CoV‐2 infection and COVID‐19 pathogenesis, as infected patients showed upregulation of the PD‐1/PD‐L1 axis and related T‐cell dysfunction,[17] potentially leading to immunosuppression. The gene discussed is CD274; the disease is COVID-19.