Individuals in quartile 4 were more likely to be older, female, non-Hispanic white, have smoked less than 100 cigarettes, be free of diabetes and hypertension, have a larger waist circumference, have higher levels of high-sensitivity CRP, and have a BMI ≥ 30 kg/m2 (p < 0.05). The gene discussed is CRP; the disease is Hypertension.