We choose the lamins A/C and B1, and the inner nuclear membrane proteins emerin and β-DG for this study because, they are involved in several cellular processes commonly deregulated in cancer, including cell signaling, chromatin organization, gene expression, nuclear structure and function and mechano- transduction [6]; and because they have previously been used as biomarkers of prostate cancer evolution [29]. The gene discussed is EMD; the disease is cancer.