APLP1 and Sensory neuropathy: Other common hits included catalase/CAT which protects neurons from oxidative stress [55], AZGP1, a regulator of energy metabolism [56], amyloid precursor-like protein 1 (APLP1), the neurotrophic amyloid precursor protein (APP) [57] and CCT4 which was linked to sensory neuropathy [58].