CD79A and myeloid sarcoma: Rojas et al. found that IgA+ plasma cells (PCs) are significantly reduced in the gut during EAE and, importantly, the removal of plasmablasts and PCs resulted in exacerbated EAE.200 A follow-up study found that IgA+ B cells traffic across the blood–brain barrier during active MS and have specificity toward MS-associated immunostimulatory bacterial strains.