The latter category included four definite AQP4+ NMO, six seronegative NMOSD, seven definite autoimmune neurological disorders (autoimmune encephalitis associated or not with a paraneoplastic syndrome; AIE/PNS), 12 suspected AIE/PNS, and 13 OIND (Figure 1, Table 1, and Supplementary Tables S3–S7). This evidence concerns the gene AQP4 and neuromyelitis optica.