What we do know is that the commensal microbiota may influence the development of lung cancer in a Kras-driven mouse model, where an antibiotic-treated group exhibited high expression of CXCL9 and CXCR3, resulting in increased recruitment of NK cells and CD8+ T cells to the tumor, highlighting the importance of the CXCL9-CXCR3 axis in lung cancer immunity (151). This evidence concerns the gene CD8A and lung cancer.