The angiogenesis and increased vascular permeability observed in wet AMD is mediated in part by an upregulation of the vascular endothelial growth factor (VEGF) (Green and Enger, 1993; Spaide and Curcio, 2010; Ambati and Fowler, 2012; Ferris et al., 2013). This evidence concerns the gene VEGFA and wet macular degeneration.