Computational analysis focusing on the gene expression data for glutamine and glutamate metabolism in different cancer types showed that the uptake of glutamine is increased by up-regulated SLC38A5 in breast invasive carcinoma (BRCA), colon adenocarcinoma (COAD), and head and neck squamous cell carcinoma (HNSC) [62]. Here, SLC38A5 is linked to colon adenocarcinoma.