Among the 40 patients with incomplete resection of tumours, the IRS values of 24 patients with a negative TMZ reaction (SD/PD) were higher than those of 16 patients with a positive reaction (CR/PR) (p < 0.001), which indicated that high expression of CBX2 is associated with TMZ chemoresistance (Figure 1E). Here, CBX2 is linked to neoplasm.