Recent studies have shown that the expression of CBX2 is closely related to the occurrence and development of osteosarcoma (Han et al., 2019), ovarian cancer (Wheeler et al., 2018), breast cancer (Chen et al., 2017), liver cancer (Mao et al., 2019) and prostate cancer (Clermont et al., 2016). The gene discussed is CBX2; the disease is breast carcinoma.