Recent studies have shown that the expression of CBX2 is closely related to the occurrence and development of osteosarcoma (Han et al., 2019), ovarian cancer (Wheeler et al., 2018), breast cancer (Chen et al., 2017), liver cancer (Mao et al., 2019) and prostate cancer (Clermont et al., 2016). This evidence concerns the gene CBX2 and Familial prostate cancer.