ABCC4 and colorectal cancer: Notably, ABCC4 expression has also been linked to the EMT process in colorectal cancer, as evidenced by its correlation with EMT markers in primary tumors datasets, and the induction of a pro-mesenchymal phenotype and increased ABCC4 expression upon overexpression of SNAI2 in HT29 colorectal adenocarcinoma cells (Kryczka et al., 2020).