STK11 and fibrosis: A recent study suggested that the RXR agonist bexarotene (Bex) attenuated DCM by inhibiting cardiac fibrosis through the activation of signaling by liver kinase B1 (LKB1) and the inhibition of p70S6K (p70 ribosomal protein S6 kinase) in STZ-induced rats (Chai et al., 2020).