Statistically, the SOC that met all four criteria simultaneously and showed significant association with sunitinib AEs were gastrointestinal disorders (n = 24452, ROR 2.27, PRR 2.04, IC 1.03, EBGM 2.04) and endocrine disorders (n = 1128, ROR 3.21, PRR 3.21, IC 1.67, EBGM 3.18). The gene discussed is UBXN11; the disease is endocrine system disorder.