The finding of our study that abemaciclib is a cost-saving option over ribociclib was not consistent with other two published findings from the two studies that we could identify to address the cost-effectiveness of abemaciclib plus aromatase inhibitors versus ribociclib plus aromatase inhibitors in HR+/HER2- advanced breast cancer patients (44, 45). Here, CYP19A1 is linked to breast carcinoma.