APOB and diabetes mellitus: After adjusting these risk factors (including diabetes, coronary heart disease, and body mass index) related to MIF, multivariable MR analysis still did not observe the causal relationship between lipid traits and MIF with genetic prediction, in which LDL-C (OR=1.07; 95% CI: 0.79-1.45; p=0.664), HDL-C (OR=1.06; 95% CI 0.81-1.38; p=0.691), TG (OR=1.03; 95% CI: 0.75-1.41; p=0.691), Apo-B (OR=1.12; 95% CI: 0.74-1.69; p=0.586), Apo-A1 (OR=1.00; 95% CI: 0.74-1.36; p=0.990).