Except for IL-8 decreased in the second trimester after infected with SARS-CoV-2, IL-2, TNF-α, TNF-β, IFN-γ, IL-4, IL-5, IL-6, IL-10, IL-17A, IL-17F, IL-22, IL-1β and IL-12p70 didn't change in the three trimesters between healthy pregnancies and pregnant women with COVID-19. The gene discussed is IL4; the disease is COVID-19.