Levels of the CD4+CD25+FOXP3+TIGIT+ T cells were 42.67% ± 4.07 in controls, 49.40% ± 9.09 in AD mice, 29.07% ± 8.38 in SA mice, and 32.12% ± 9.76 in HA mice (Figure 3F). The gene discussed is CD4; the disease is Alzheimer disease.