CLPTM1L and lung cancer: Genome-wide association studies (GWAS) have pinpointed specific single nucleotide polymorphisms (SNPs) within the CLPTM1L gene (such as rs401681 and rs402710) as intricately intertwined with the onset and progression of various malignancies spanning lung cancer, breast cancer, pancreatic cancer, nasopharyngeal carcinoma and bladder cancer among others (3,7,12).