According to the results, the expressions of TB (OR = 1.042, p = 0.037), mt-ND1 (OR = 0.00, p = 0.021), mt-CO1 (OR = 0,004, p = 0.004), and mt-ATP6 (OR = 0.007, p = 0.008) revealed persistent strength in assessing clinical outcomes of sepsis, which could serve as independent factors in early identifying non-survivors. This evidence concerns the gene MT-ND1 and Sepsis.