STING1 and colitis: To further investigate whether the activation of IL-12 signaling in colitis is dependent on STING, bone marrow-derived macrophages (BMDMs) and bone marrow-derived dendritic cells (BMDCs) isolated from Tmem173fl/fl mice and Tmem173iΔmye mice were treated with STING agonist Vadimezan (DMXAA) and RNA-seq analysis was applied.