The mRNA levels of Tmem173, tumor favoring inflammatory genes and IL-12 family genes were all remarkably increased in the tumor of Tmem173iΔmye mice (Figure 7M), in line with suppressed STING-related type I IFN pathways, and impaired antigen presentation, and macrophage and DC activation (Figure S12B-D). Here, STING1 is linked to neoplasm.