In myocardial fibrosis caused by myocardial infarction, Yu et al. reported a novel DC-expressed circRNA called circSnx5, which would inhibit DC maturation via miR-544/SOCS1; it also directly affects the nuclear translocation of PU.1, regulates the expression of downstream MHC class II, and modulates the function of DCs 142. Here, SOCS1 is linked to Myocardial fibrosis.