In myocardial fibrosis, has-circ-0000672 can act as a ceRNA, targeting miR-516a-5p and decreasing its expression, resulting in decreased binding of miR-516a-5p to its target gene, TRAF6 mRNA 3'-UTR, and facilitating the development of myocardial fibrosis 184. Here, TRAF6 is linked to Myocardial fibrosis.