In addition, H. pyloriWT infection totally disrupted the negative impact of CYP19A1 on CYP11A1: CYP11A1 was immune from the influence of CYP19A1 and could maintain a high expression level in GC cells infected with H. pyloriWT(Figure 4C, Figure 4E, Figure S4B and Figure S4D). This evidence concerns the gene CYP19A1 and infection.