Conversely, the pro‐tumor phenotype (N2) of TANs is characterized by high levels of CCL2, CCL3, CCL4, CCL8, CCL12, CCL17, CXCL1, CXCL2, CXCL8, and CXCL16 chemokines.[36] To confirm the phenotypic effects on HL‐60 cells cultured in the conditioned medium derived from shNKX2‐1‐transfected H1975 and HCC827 cells, we conducted qRT‐PCR analysis. This evidence concerns the gene CXCL2 and neoplasm.