VEGFA and myocardial infarction: Guo et al. further proposed that Sal B alone may play a synergetic role in the cytoprotection of BMSCs and that Sal B-BMSCs transplantation can significantly improve the heart function of rats with MI by enhancing angiogenesis and the production of beneficial cytokines, such as vascular endothelial growth factor (VEGF) and angiopoietin 1 (Ang-1) [60].