In our nomenclature, different human IBD patient fecal pools are called Human Microbiota (HM1 or HM2) (shown in Figure S1A), feces from HMA WT mice are called Non-Inflamed Mouse-adapted Microbiota (NIMM), and feces from HMA Il-10−/− mice are called inflamed mouse-adapted microbiota (IMM) (Fig. 1A). This evidence concerns the gene IL10 and inflammatory bowel disease.