SNX8 and COVID-19–associated multisystem inflammatory syndrome in children: To test this hypothesis, T cells from nine patients with MIS-C (eight from SNX8 autoantibody-positive patients and one who was SNX8 autoantibody negative) and ten at-risk controls (chosen randomly) were exposed to a pool of 15-mer peptides with 11-amino acid overlaps tiling the full-length human SNX8 protein.