Age, Ischaemic Heart Disease, COPD, CPAP duration, Hospital LOS, WBC count, D-dimer, CRP, PEEP, FiO2, PF ratio, Respiratory rate, A-a O2 gradient, GCS, ROX index, mROX index, HACOR score PaCO2,. The gene discussed is CRP; the disease is chronic obstructive pulmonary disease.