NLRP3 and liver dysplastic nodule: Studies have shown that Danggui Buxue decoction can elevate the levels of PGC-1α, MnSOD mRNA and protein expression, reduce the levels of NLRP3, IL-1β mRNA and protein expression improve the mitochondrial dysfunction of podocytes in DN rats, alleviate oxidative stress, mitigate the inflammatory response, and slow down the progression of DN (63).