PPARGC1A and kidney disorder: Danggui Buxue decoction is composed of Astragali Radix and Angelicae sinensis radox in a 5:1 dosage ratio, which has the effect of tonifying Qi and generating blood, and resolving blood stasis.It has been reported that peroxisome proliferator-activated receptor-γ coactivator-1-α (PGC-1α) is a major regulator of mitochondrial biogenesis, and it participates in mitochondrial biogenesis in renal diseases by orchestrating transcriptional mechanisms.