Analysis of CTCs expressing vimentin [21] as a mesenchymal marker and CD133 [21], CD90 [21,[32], [33], [34]], and EpCAM [21,33,35] as stem cell markers in HCC has been reported to be useful for early diagnosis, prognosis prediction, and determination of therapeutic efficacy. The gene discussed is THY1; the disease is hepatocellular carcinoma.