In summary, m6A methylation regulates the release of certain asthma inflammatory factors, the contraction of airway smooth muscle cells, and the development of asthma subtypes, which are further mediated by regulatory factors such as YTHDF1, YTHDF2, YTHDC1, FTO, and METTL3, which have emerged as new targets for the treatment and prognosis of asthma. Here, METTL3 is linked to asthma.