ALKBH5 expression was downregulated in neutrophils sampled from septicemia mice, and ALKBH5-m6A methylation maintained the intrinsic ability of neutrophils to undergo chemotaxis toward the site of infection, ensuring their antimicrobial and immune functions, due to the function of ALKBH5-m6A in maintaining CXCR2 mRNA stability (Liu et al., 2022). This evidence concerns the gene ALKBH5 and Sepsis.