(peroxisome proliferator-activated receptor agonist OR PPAR OR bezafibrate OR fenofibrate OR seladelpar OR MBX-8025 OR elafibranor OR saroglitazar).af. AND (primary biliary cholangitis OR primary biliary cirrhosis OR PBC).af. AND (randomised controlled trial OR controlled clinical trial OR randomised OR randomly OR RCT).af The gene discussed is PPARA; the disease is biliary liver cirrhosis.