In a separate study, 22 endometriosis-related immune genes emerged from the overlap of 1 116 DEGs, featuring nine immune-related hub genes (BST2, CCL13, CD86, CSF1, FAM3C, GREM1, ISG20, PSMB8, S100A11) and nine ARG hub genes (GSK3A, HTR2B, RAB3GAP1, ARFIP2, BNIP3, CSF1, MAOA, PPP1R13L, SH3GLB2) (16). The gene discussed is GREM1; the disease is endometriosis.