Median [IQR] serum NfL was significantly higher in the LRRK2 CSFasynSAA- (17.10 [13.60–22.10]) compared to the LRRK2 CSFasynSAA+ group (10.50 [8.43–14.70], p<0.001) and the sPD group (12.60 [9.60–16.10], p<0.001). Here, NEFL is linked to Platelet storage pool disease.