For example, neurogranin (NRGN) is a widely studied postsynaptic protein, showing higher levels with worse memory performance in prodromal AD(Headley et al., 2018), although contradicting results have been found for memory associations in cognitively normal (CN) individuals(Dulewicz et al., 2020; Headley et al., 2018; Kvartsberg et al., 2015) and in AD dementia(Nilsson et al., 2021; Tarawneh et al., 2016). Here, NRGN is linked to Alzheimer disease.