SCIN and neoplasm: Figure 8D illustrated that the tumor growth diminished in mice subcutaneously inoculated with HepG2 LV-shSCIN cells, whereas the tumors grew progressively in mice injected with HepG2 LV-shNC cells or HepG2 cells (Figure 8E). To address the impact of SCIN knockdown on survival time, the survival rate of experimental animals was recorded post tumor cells inoculation. Expectably, the suppression of SCIN prolonged survival time of mice models (Figure 8F).