Figure 5C clearly shows that a total of 138 mutations were found between amino acid 0 and 715, including 100 missense, 22 truncating, 1 inframe, 12 splice, and 3 fusion mutations. Among them, S673F and S381Ywere most frequently mutated. The overall survival rate (P = 6.013e-03), disease-specific (P = 1.248e-03), and progression-free (P = 0.0121) survival of Sarcoma patients with unaltered SCIN changes were better, but t no correlation was seen between SCIN gene mutation and prognosis in other tumors (Figure 5D). Here, SCIN is linked to sarcoma.