The KEGG analysis indicated that these DEGs were enriched in cell-matrix pathways such as “Cell adhesion molecules” and “ECM receptor interaction,” as well as cell signaling pathways such as “cAMP,” “cGMP-PKG,” “Rap1”, and “PI3K-Akt” (Figure 4C), which are closely connected to the occurrence and development of hypoxia, inflammation, and cancer (34–37). The gene discussed is AKT1; the disease is cancer.