These cytokines interact with one another and contribute to the occurrence of AAV disease through pathogenic pathways, such as cytokine–cytokine receptor interaction, viral protein interaction with cytokine and cytokine receptor, chemokine signaling pathway, IL-17 signaling pathway, rheumatoid arthritis, JAK-STAT signaling pathway, TNF signaling pathway, and other signaling pathways. The gene discussed is SOAT1; the disease is rheumatoid arthritis.