*USP9X binds to FLT3‐ITD and its downregulation cooperates with WP1130 DUB inhibitor to promote FLT3‐ITD degradation and apoptosis of AML cells [23]. *USP9X deubiquitinates and stabilises ALKBH5 and promotes cell survival in AML cellular and murine models [34]. The gene discussed is FLT3; the disease is acute myeloid leukemia.