Meanwhile, we used GEO (https://www.ncbi.nlm.nih.gov/mesh/) and TCGA database (https://www.cancer.gov/ccg/research/genome‐sequencing/tcga) for external validation and discovered that HIF‐1α and NRF2 were BC tumour promoter which is consistent with our study (Figure S3H and I). Here, HIF1A is linked to neoplasm.