Compared with those in the HFD+vector group, mice injected with AAV9‐TBG‐circ‐SLC9A6 or AAV9‐TBG‐SLC9A6‐126aa exhibited more severe dyslipidemia; on the other hand, the levels of proteins associated with lipid homeostasis were unaltered in the mice injected with AAV9‐TBG‐mut‐circ‐SLC9A6 (Figure 4I). Here, SLC9A6 is linked to metabolic syndrome.