ABCA1 is responsible for the efflux of isopentenyl pyrophosphate (IPP), a small isoprenoid intermediate in cholesterol synthesis and an endogenous activator of the cytotoxic Vγ9Vδ2 T-lymphocytes [9]: through this mechanism, ABCA1 enhances tumor immuno-killing by this T-lymphocyte subset, while tumors with low ABCA1 are immuno-resistant [10, 11]. Here, ABCA1 is linked to neoplasm.