CD34 and neoplasm: In terms of tumor volume reduction, the effect of NZ + PT was greater in shTFEB tumors than WT tumors implanted Hu-CD34+ mice (final tumor volume: 24.15 ± 3.97 in shTFEB tumors versus 39.09 ± 4.57 in WT tumors), while it did not differ for tumors implanted in NSG mice (Supplemental Fig. S12B).