CRP and congenital rubella syndrome: In multivariable analyses, based on parameters that were most frequently selected by bootstrap analysis, bulky disease, a platelet count < 150 G/L and a CRP level > 30 mg/L were significantly associated with a higher risk of grade ≥ 3 CRS, while achieving a CR or a PR after bridging (compared with no bridging therapy or SD/PD after bridging) was predictive of a decreased risk (Supplementary Table S6).